Van de Ven Double Ends Everton's Run at Brand New Home Ground
Micky van de Ven emerged as the first defender to net two goals in a English top-flight game for Spurs since Jan Vertonghen in March 2013.
At a glance
Micky Van de Ven nods home two times in first half
Everton's Jake O'Brien has goal disallowed after video check
Senegalese midfielder scores final goal in 89th minute
The defeat is the Merseyside club's initial at their new ground
Micky van de Ven scored on two occasions as Tottenham extended their winning streak in away games in the top division and delivered Everton their initial loss at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after more than a century at the end of the previous campaign.
But Spurs captain the Dutchman struck twice from set-pieces in the first half to put their impressive record at jeopardy, and they were unable to mount a comeback before the midfielder - set up by ex-Everton forward the Brazilian - nodded in a final goal to put the game to bed.
Jake O'Brien thought he had equalized the tally a short while after the defender's first goal, directing a powerful header past Guglielmo Vicario from an set-piece.
Beto, in the meantime, failed to convert a handful of opportunities, while the Italian goalkeeper made a succession of fine stops to guarantee Tottenham went five matches on the road without defeat in the English top flight.
But the VAR intervened, instructing the match official to review the score on the pitchside monitor and the official decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
This victory elevates Thomas Frank's side into third place in the division, a handful of points off local foes and table-toppers Arsenal.
The Merseyside club stay 14th and sit half a dozen points ahead of the drop zone.
Spurs breakdown: Van de Ven fulfils duties at both ends of the field
Following a drab weekday performance in the Champions League against Monaco, where they mustered a mere two shots on target, the manager opted for Randal Kolo Muani up front instead of former Toffees player the Brazilian.
The new arrival was failed to make much of an impact before being replaced for the substitute after an hour on the field, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman converted into an offensive threat to be feared.
Spurs' first goal came from a well-worked set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to head home.
And the captain - filling in as skipper in the Argentine's unavailability - notched his next goal in first-half stoppage time as he outjumped the England keeper to nod in.
The Dutchman was just as impressive in defensive duties, combining well with his defensive colleague as the duo handled superbly with the 34 crosses sent their way by the opposition.
Toffees breakdown: Everton missing striker's instinct
Everton's new home had been a happy hunting ground, but it appears the novelty may have faded slightly and supporters flocked to the exits after the midfielder's final goal for Tottenham.
The end in Everton's winning streak at home won't be a major concern for the manager, but their attacking woes are.
Beto and the other striker - the Toffees' two established centre-forwards - had netted just one league goal between them before the weekend's match.
And they were unable to contribute to that miserable record on a damp and dreary night on Merseyside.
The striker's performance was summed up when he chose to overhead kick a golden opportunity from near the goal, even with having room and time to reposition for a simpler attempt that would have tested the keeper.
The substitute, as well, failed to influence the game after replacing the starter in the second half.
It wasn't for a lack of opportunity. Most of the home side's offensive moves came through Grealish and Ndiaye, who tirelessly whipped dangerous balls into the Tottenham penalty area.
What next for these two sides?
The Toffees: Moyes' men travel to the Stadium of Light in the Premier League on Monday, 3 November at 20:00 GMT.
Tottenham: Spurs go to Newcastle's ground on late October for their fourth-round League Cup match against Newcastle.